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1-(3,5-二-o-乙酰基-beta-d-呋喃核糖)-4-(1,2,4-噻唑-l-基)-5-甲基-2-嘧啶酮

更新时间:2024-01-09 19:25:13

1-(3,5-二-o-乙酰基-beta-d-呋喃核糖)-4-(1,2,4-噻唑-l-基)-5-甲基-2-嘧啶酮结构式
1-(3,5-二-o-乙酰基-beta-d-呋喃核糖)-4-(1,2,4-噻唑-l-基)-5-甲基-2-嘧啶酮结构式
委托求购
常用名 1-(3,5-二-o-乙酰基-beta-d-呋喃核糖)-4-(1,2,4-噻唑-l-基)-5-甲基-2-嘧啶酮 英文名 1-(3,5-DIMETHYL-4-ETHYL-PYRROL-2-YL)-3-(3,5-DIMETHYL-4-ETHYL-PYRROLIUM-2-YLIDENE)-CYCLOBUTEN-2-ONE-4-OLATE
CAS号 80991-41-9 分子量 393.35100
密度 1.51g/cm3 沸点 578.1ºC at 760 mmHg
分子式 C16H19N5O7 熔点 N/A
MSDS N/A 闪点 303.4ºC

 名称

中文名 1-(3,5-二-o-乙酰基-beta-d-呋喃核糖)-4-(1,2,4-噻唑-l-基)-5-甲基-2-嘧啶酮
英文名 1-(3,5-DI-O-ACETYL-β-D-RIBOFURANOSYL)-4-(1,2,4-TRIAZOL-L-YL)-5-METHYLPYRMIDIN-2-ONE

 物理化学性质

密度 1.51g/cm3
沸点 578.1ºC at 760 mmHg
分子式 C16H19N5O7
分子量 393.35100
闪点 303.4ºC
精确质量 393.12800
PSA 147.66000
折射率 1.659

 合成线路

~93%

1-(3,5-二-o-乙酰基-beta-d-呋喃核糖)-4-(1,2,4-噻唑-l-基)-5-甲基-2-嘧啶酮结构式

1-(3,5-二-o-乙酰基-...

80991-41-9

文献:Felczak; Miazga; Poznanski; Bretner; Kulikowski; Dzik; Golos; Zielinski; Ciesla; Rode Journal of Medicinal Chemistry, 2000 , vol. 43, # 24 p. 4647 - 4656

~66%

1-(3,5-二-o-乙酰基-beta-d-呋喃核糖)-4-(1,2,4-噻唑-l-基)-5-甲基-2-嘧啶酮结构式

1-(3,5-二-o-乙酰基-...

80991-41-9

文献:Reese, Colin B.; Richards, Keith H. Tetrahedron Letters, 1985 , vol. 26, # 18 p. 2245 - 2248

~65%

1-(3,5-二-o-乙酰基-beta-d-呋喃核糖)-4-(1,2,4-噻唑-l-基)-5-甲基-2-嘧啶酮结构式

1-(3,5-二-o-乙酰基-...

80991-41-9

文献:Reese, Colin B.; Richards, Keith H. Tetrahedron Letters, 1985 , vol. 26, # 18 p. 2245 - 2248

~88%

1-(3,5-二-o-乙酰基-beta-d-呋喃核糖)-4-(1,2,4-噻唑-l-基)-5-甲基-2-嘧啶酮结构式

1-(3,5-二-o-乙酰基-...

80991-41-9

文献:Roelen, H. C. P. F.; Brugghe, H. F.; Elst, H. van den; Marel, G. A. van der; Boom, J. H. van Recueil des Travaux Chimiques des Pays-Bas, 1992 , vol. 111, # 2 p. 99 - 104

~%

1-(3,5-二-o-乙酰基-beta-d-呋喃核糖)-4-(1,2,4-噻唑-l-基)-5-甲基-2-嘧啶酮结构式

1-(3,5-二-o-乙酰基-...

80991-41-9

文献:Rodriguez-Tanty; Higginson-Clarke; Hernandez; Perez; Velez- Castro; Riveron; Macias Nucleosides and Nucleotides, 1997 , vol. 16, # 4 p. 455 - 467

~%

1-(3,5-二-o-乙酰基-beta-d-呋喃核糖)-4-(1,2,4-噻唑-l-基)-5-甲基-2-嘧啶酮结构式

1-(3,5-二-o-乙酰基-...

80991-41-9

文献:Reese, Colin B.; Richards, Keith H. Tetrahedron Letters, 1985 , vol. 26, # 18 p. 2245 - 2248

~21%

1-(3,5-二-o-乙酰基-beta-d-呋喃核糖)-4-(1,2,4-噻唑-l-基)-5-甲基-2-嘧啶酮结构式

1-(3,5-二-o-乙酰基-...

80991-41-9

文献:Reese, Colin B.; Richards, Keith H. Tetrahedron Letters, 1985 , vol. 26, # 18 p. 2245 - 2248

~%

1-(3,5-二-o-乙酰基-beta-d-呋喃核糖)-4-(1,2,4-噻唑-l-基)-5-甲基-2-嘧啶酮结构式

1-(3,5-二-o-乙酰基-...

80991-41-9

文献:Wallis, Mark P.; Mahmood, Naheed; Fraser, William Farmaco, 1999 , vol. 54, # 1-2 p. 83 - 89