36062-07-4

• 常用中文名：八氢姜黄素
• 常用英文名：Octahydrocurcumin
• CAS号：36062-07-4
• 分子式：C₂₁H₂₈O₆
• 分子量：376.443
• 相关类别： 研究领域 其他
• 发布时间：2018-05-14 08:00:00
• 更新时间：2024-01-02 17:05:30
• 八氢姜黄素(Octahydrocurcumin)是姜黄素的氢化衍生物,姜黄素的代谢物。
• 在动物体内有利胆作用。对泥沙状胆结石有一定溶解作用。
   

名称

• 中文名: 八氢姜黄素
• 英文名: 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanediol
• 英文别名: 1,7-Bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-diol; Curcumin bis-acetate; octahydrocurcumin; Curcumin 4,4'-diacetate; 1,6-Heptadiene-3,5-dione,1,7-bis(4-(acetyloxy)-3-methoxyphenyl); 1,7-bis(4-acetoxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione; hexahydrocurcuminol; diacetyldiferuloylmethane; diacetylcurcumin; 3,5-Heptanediol, 1,7-bis(4-hydroxy-3-methoxyphenyl)-; 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanediol; curcumin acetic acid ester (diacetylated); 1,7-bis(4-acetoxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione; 4,4'-Diacetylcurcumin; Di-O-Acetylcurcumin; Acetic acid,4-[7-(4-acetoxy-3-methoxy-phenyl)-3,5-dioxo-hepta-1,6-dienyl]-2-methoxy-phenyl ester; 1,7-bis-(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 623.5±55.0 °C at 760 mmHg
• 分子式: C₂₁H₂₈O₆
• 分子量: 376.443
• 闪点: 330.9±31.5 °C
• 精确质量: 376.188599
• PSA: 99.38000
• LogP: 1.73
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.592
• 储存条件: -20°C

生物活性

• 描述: 八氢姜黄素(Octahydrocurcumin)是姜黄素的氢化衍生物,姜黄素的代谢物。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他
  天然产物 >> 酚类
• 参考文献:

  [1]. Deters M, et al. Different curcuminoids inhibit T-lymphocyte proliferation independently of their radical scavenging activities. Pharm Res. 2008 Aug;25(8):1822-7.

  [2]. Zhao F, et al. Curcumin and its major metabolites inhibit the inflammatory response induced by lipopolysaccharide: Translocation of nuclear factor-κB as potential target. Mol Med Rep. 2015 Apr;11(4):3087-93.

  [3]. Somparn P, et al. Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives. Biol Pharm Bull. 2007 Jan;30(1):74-8.