34465-83-3

34465-83-3 structure

Name: Collinin
Chemical Name: collinin
CAS Number: 34465-83-3
Molecular Formula: C₂₀H₂₄O₄
Molecular Weight: 328.40200
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-06-26 11:39:41
Modify Date: 2024-02-04 22:57:40
Collinin is a anti-tubercular agent, it can be isolated from leaves of Z. schinifolium. Collinin has an excellent anti-tuberculosis effect against multidrug-resistant (MDR), extensively drug-resistant (XDR) strains[1].

Name	collinin
Synonyms	7-(3,7-dimethyl-octa-2,6-dienyloxy)-8-methoxy-chromen-2-one 7-(3,4-dichloro-phenyl)-2,4,5,7-tetrahydro-3H-[1,3]diazepino[2,1-a]isoindol-7-ol 2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethanol 1-Piperazineethanol,4-(3-(trifluoromethyl)phenyl) 2-(4-(3-(Trifluoromethyl)phenyl)-1-piperazinyl) ethanol m-Trifluoro-methyl-4-phenyl-1-piperazinoethanol

Description	Collinin is a anti-tubercular agent, it can be isolated from leaves of Z. schinifolium. Collinin has an excellent anti-tuberculosis effect against multidrug-resistant (MDR), extensively drug-resistant (XDR) strains[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Collinin在培养基中显著抑制 MDR 和 XDR 结核分枝杆菌的生长，50% 最低抑制浓度 (MIC50s) 为 3.13-6.25 µg/mL[1]。 Collinin抑制 Raw264.7 和 A549 细胞内药敏和耐药结核的生长，MIC50 为6.25-12.50 µg/mL[1]。
References	[1]. Kim S, et al. In vitro activity of collinin isolated from the leaves of Zanthoxylum schinifolium against multidrug- and extensively drug-resistant Mycobacterium tuberculosis. Phytomedicine. 2018 Jul 15;46:104-110.