2310286-60-1

2310286-60-1 structure

Name: IDO1/2-IN-1 hydrochloride
Chemical Name: IDO1/2-IN-1 hydrochloride
CAS Number: 2310286-60-1
Molecular Formula: C₁₆H₁₉BrClFN₈O₄
Molecular Weight: 521.73
Catalog: Signaling Pathways Metabolic Enzyme/Protease Indoleamine 2,3-Dioxygenase (IDO)
Create Date: 2022-06-28 15:53:06
Modify Date: 2024-01-09 17:51:09
IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active[1].

Name	IDO1/2-IN-1 hydrochloride

Description	IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO)
References	[1]. He X, et al. Discovery of the First Potent IDO1/IDO2 Dual Inhibitors: A Promising Strategy for Cancer Immunotherapy. J Med Chem. 2021;64(24):17950-17968.

Molecular Formula	C₁₆H₁₉BrClFN₈O₄
Molecular Weight	521.73