1312954-58-7

1312954-58-7 structure

Name: Fotagliptin
Chemical Name: Fotagliptin
CAS Number: 1312954-58-7
Molecular Formula: C₁₇H₁₉FN₆O
Molecular Weight: 342.37
Catalog: Signaling Pathways Metabolic Enzyme/Protease Dipeptidyl Peptidase
Create Date: 2023-04-20 19:20:44
Modify Date: 2024-01-16 12:53:57
Fotagliptin is a Dipeptidyl Peptidase IV (DPP-4) inhibitor (IC50=2.27 nM). Fotagliptin displays great security in rat and dog. Fotagliptin can be used for Type 2 diabetes mellitus research[1].

Name	Fotagliptin

Description	Fotagliptin is a Dipeptidyl Peptidase IV (DPP-4) inhibitor (IC50=2.27 nM). Fotagliptin displays great security in rat and dog. Fotagliptin can be used for Type 2 diabetes mellitus research[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Dipeptidyl Peptidase Research Areas >> Metabolic Disease
Target	DPP-4:2.27 nM (IC50)
In Vivo	Fotagliptin (33 mg/kg 或 110 mg/kg) 在不同剂量下对大鼠和狗是安全的[1]。
References	[1]. Wang Z, et al. Development and validation of a UPLC-MS/MS method for simultaneous determination of fotagliptin and its two major metabolites in human plasma and urine. Bioanalysis. 2017 Feb;9(4):381-393.

Molecular Formula	C₁₇H₁₉FN₆O
Molecular Weight	342.37