367518-31-8

367518-31-8 structure

Name: Galanin (2-11) amide trifluoroacetate salt
Chemical Name: trp-thr-leu-asn-ser-ala-gly-tyr-leu-leu-nh2
CAS Number: 367518-31-8
Molecular Formula: C₅₄H₈₁N₁₃O₁₄
Molecular Weight: 1136.30
Catalog: Signaling Pathways GPCR/G Protein Neuropeptide Y Receptor
Create Date: 2016-02-15 17:31:47
Modify Date: 2024-01-09 11:54:58
AR-M1896 is a GalR2 selective agonist with a binding IC50 of 1.76 nM for rat GalR2. AR-M1896 can be used for the research of acute myocardial infarction and neuropathic pain[1][2].

Name	trp-thr-leu-asn-ser-ala-gly-tyr-leu-leu-nh2
Synonyms	Dynole 34-2 Galanin (2-11)

Description	AR-M1896 is a GalR2 selective agonist with a binding IC50 of 1.76 nM for rat GalR2. AR-M1896 can be used for the research of acute myocardial infarction and neuropathic pain[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor
Target	IC50: 1.76 nM (rat GalR2), 879 nM (hGalR1)[1]
References	[1]. Liu HX, et al. Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective actions via GalR1 and GalR2 receptors. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9960-4. [2]. Serebryakova L, et al. Galanin and its N-terminal fragments reduce acute myocardial infarction in rats. Peptides. 2019 Jan;111:127-131.