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59456-70-1

59456-70-1 structure
59456-70-1 structure
  • Name: Nikkomycin Z
  • Chemical Name: nikkomycin Z
  • CAS Number: 59456-70-1
  • Molecular Formula: C20H25N5O10
  • Molecular Weight: 495.44000
  • Catalog: Signaling Pathways Anti-infection Fungal
  • Create Date: 2018-07-14 18:56:27
  • Modify Date: 2024-01-03 11:45:43
  • Nikkomycin Z, a nucleoside-peptide, is a selective competitive chitin synthesis inhibitor. Nikkomycin Z has antifungal effects and acts as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine[1].

Name nikkomycin Z
Synonyms Nikkomycin Z
MFCD00869648
Description Nikkomycin Z, a nucleoside-peptide, is a selective competitive chitin synthesis inhibitor. Nikkomycin Z has antifungal effects and acts as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine[1].
Related Catalog
References

[1]. R Kovács, et al. Synergistic Effect of Nikkomycin Z With Caspofungin and Micafungin Against Candida Albicans and Candida Parapsilosis Biofilms. Lett Appl Microbiol. 2019 Oct;69(4):271-278.

Density 1.646 g/cm3
Molecular Formula C20H25N5O10
Molecular Weight 495.44000
Exact Mass 495.16000
PSA 250.32000
Index of Refraction 1.678

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BA2928200
CHEMICAL NAME :
beta-D-Allofuranuronic acid, 5-((2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-met hyl- 1-oxobutyl)amino)-1,5-dideoxy-1-(3,4-dihydro-2,4-diox o-1(2H)-pyrimidinyl)-, (2S-(2R*,3R*,4R*))-
CAS REGISTRY NUMBER :
59456-70-1
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H25-N5-O10
MOLECULAR WEIGHT :
495.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 44,1709,1980
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
RTECS BA2928200