71184-20-8

71184-20-8 structure

Name: Carbodine
Chemical Name: 2-hydroxy-5-(2,4,4-trimethylpentan-2-yl)benzenesulfonic acid
CAS Number: 71184-20-8
Molecular Formula: C₁₀H₁₅N₃O₄
Molecular Weight: 286.38700
Catalog: Signaling Pathways Anti-infection Influenza Virus
Create Date: 2017-01-18 00:18:56
Modify Date: 2024-01-02 13:38:38
Carbodine (Carbocyclic cytidine) is a broad-spectrum antiviral agent active against DNA viruses, (+)RNA viruses, (-)RNA viruses, paramyxo, rhabdo and (+/-)RNA viruses, targets CTP synthetase that converts UTP to CTP. Carbodine (Carbocyclic cytidine) possesses significant antiviral activity against influenza virus types A0/PR-8/34 and A2/Aichi/2/68 in vitro[1][2].

Name	2-hydroxy-5-(2,4,4-trimethylpentan-2-yl)benzenesulfonic acid
Synonyms	2-Hydroxy-5-(1,1,3,3-tetramethylbutyl)benzenesulfonic acid p-Isooctylphenol-2-sulfonic acid D-(-)-carbodine Benzenesulfonic acid,2-hydroxy-5-(1,1,3,3-tetramethylbutyl) (-)-carbodine (1R,2S,3R,4R)-1-[2,3-dihydroxy-4-(hydroxymethyl)-cyclopentan-1-yl]cytosine

Description	Carbodine (Carbocyclic cytidine) is a broad-spectrum antiviral agent active against DNA viruses, (+)RNA viruses, (-)RNA viruses, paramyxo, rhabdo and (+/-)RNA viruses, targets CTP synthetase that converts UTP to CTP. Carbodine (Carbocyclic cytidine) possesses significant antiviral activity against influenza virus types A0/PR-8/34 and A2/Aichi/2/68 in vitro[1][2].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
References	[1]. De Clercq E, et al. Broad-spectrum antiviral activity of carbodine, the carbocyclic analogue of cytidine. Biochem Pharmacol. 1990 Jan 15;39(2):319-25. [2]. Shannon WM, et al. Evaluation of carbodine, the carbocyclic analog of cytidine, and related carbocyclic analogs of pyrimidine nucleosides for antiviral activity against human influenza Type A viruses. Antimicrob Agents Chemother. 1981 Dec;20(6):769-76.