三氯乙腈
三氯乙腈用途
三氯乙腈名称
[ CAS 号 ]:
545-06-2
[ 中文名 ]:
三氯乙腈
[ 英文名 ]:
Trichloroacetonitrile
[中文别名 ]:
[英文别名 ]:
- EINECS 208-885-7
- Acetonitrile, 2,2,2-trichloro-
- UNII:6397DL8869
- Trichloroacetonitrile
- 2,2,2-trichloroacetonitrile
- MFCD00001842
三氯乙腈生物活性
[ 描述 ]:
[ 相关类别 ]:
[参考文献]
三氯乙腈物理化学性质
[ 密度 ]:
1.6±0.1 g/cm3
[ 沸点 ]:
85.7±0.0 °C at 760 mmHg
[ 熔点 ]:
-42 °C
[ 分子式 ]:
C2Cl3N
[ 分子量 ]:
144.387
[ 闪点 ]:
10.5±20.2 °C
[ 精确质量 ]:
142.909637
[ PSA ]:
23.79000
[ LogP ]:
2.54
[ 外观性状 ]:
无色至淡黄色液体
[ 蒸汽压 ]:
68.6±0.1 mmHg at 25°C
[ 折射率 ]:
1.489
[ 储存条件 ]:
库房通风低温干燥,与酸类、氧化剂、食品添加剂分开存放
[ 稳定性 ]:
Stable, but water sensitive. Incompatible with acids, water, steam. May hydrolyze in alkali or acid conditions. Flammable.
[ 水溶解性 ]:
<0.1 g/100 mL at 21.5°C | <0.1 g/100 mL at 21.5 ºC
三氯乙腈MSDS
三氯乙腈毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AM2450000
- CHEMICAL NAME :
- Acetonitrile, trichloro-
- CAS REGISTRY NUMBER :
- 545-06-2
- BEILSTEIN REFERENCE NO. :
- 0605572
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 23
- MOLECULAR FORMULA :
- C2-Cl3-N
- MOLECULAR WEIGHT :
- 144.38
- WISWESSER LINE NOTATION :
- NCXGGG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 250 ppm/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 311 ppm/5H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 900 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 311 ppm/5H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 97500 ug/kg
- SEX/DURATION :
- female 6-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system Reproductive - Specific Developmental Abnormalities - urogenital system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 97500 ug/kg
- SEX/DURATION :
- female 6-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 455 mg/kg
- SEX/DURATION :
- female 6-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 825 mg/kg
- SEX/DURATION :
- female 7-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 15 umol/L
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 5,1065,1985 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,269,1991 IARC Cancer Review:Human No Available Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,269,1991 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,269,1991
三氯乙腈安全信息
[ 符号 ]:
GHS06, GHS09
[ 信号词 ]:
Danger
[ 危害声明 ]:
H301 + H311 + H331-H315-H319-H411
[ 警示性声明 ]:
Missing Phrase - N15.00950417-P261-P280-P302 + P352 + P312-P304 + P340 + P312-P403 + P233
[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
T:Toxic
[ 风险声明 (欧洲) ]:
R23/24/25;R51/53
[ 安全声明 (欧洲) ]:
S45-S61
[ 危险品运输编码 ]:
UN 3276 6.1/PG 3
[ WGK德国 ]:
3
[ RTECS号 ]:
AM2450000
[ 包装等级 ]:
II
[ 危险类别 ]:
8
[ 海关编码 ]:
29269095
三氯乙腈合成路线
三氯乙腈上下游产品
三氯乙腈上游产品
三氯乙腈下游产品
三氯乙腈海关
[ 海关编码 ]: 2926909090
[ 中文概述 ]:
2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
三氯乙腈文献
Toxicol. Lett. 7(4-5) , 321-7, (1981)
Urines collected from rats injected with acrylonitrile (ACN) were mutagenic towards Salmonella typhimurium TA1530; this activity was reduced when the animals were pretreated by pyrazole (inhibitor of ...
Trichloroacetonitrile.IARC Monogr. Eval. Carcinog. Risks Hum. 71 Pt 3 , 1533-7, (1999)
Teratogenic effects of trichloroacetonitrile in the Long-Evans rat.
Teratology 38(2) , 113-20, (1988)
Trichloroacetonitrile (TCAN) is among a number of contaminants found in drinking water produced by reactions of chlorine with background organic material. Long-Evans rats were intubated with TCAN (0, ...
相关化工产品/化学物质:
推荐生产厂家/供应商:
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥458.0/500g
¥138.0/100g
联系人:刘佳
产品详情:三氯乙腈
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥69.0/50g
¥437.0/500g
¥47.0/25g
¥299.0/250g
联系人:阿拉丁李高志
产品详情:三氯乙腈
查看所有供应商请点击:
相关化合物
【三氯乙腈】化源网提供三氯乙腈CAS号545-06-2,三氯乙腈MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询三氯乙腈上化源网,专业又轻松。>>电脑版:三氯乙腈
标题:三氯乙腈_MSDS_用途_密度_三氯乙腈CAS号【545-06-2】_化源网 地址:https://m.chemsrc.com/mip/cas/545-06-2_331160.html