氨基甲酰-PAF(C16)

氨基甲酰-PAF(C16)用途

Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH.

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氨基甲酰-PAF(C16)名称

[ CAS 号 ]:
91575-58-5

[ 中文名 ]:
氨基甲酰-PAF(C16)

[ 英文名 ]:
1-O-HEXADECYL-2-N-METHYLCARBAMYL-SN-GLYCERO-3-PHOSPHOCHOLINE

[英文别名 ]:

MFCD00065891
Methylcarbamol
mc-PAF
mcPlatelet activating factor
cPAF

氨基甲酰-PAF(C16)物理化学性质

[ 分子式 ]:
C₂₆H₅₅N₂O₇P

[ 分子量 ]:
538.698

[ 精确质量 ]:
538.374695

[ PSA ]:
115.96000

[ LogP ]:
3.92

[ 储存条件 ]:
-20°C，密闭，干燥

氨基甲酰-PAF(C16)安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

氨基甲酰-PAF(C16)文献

Staphylococcal lipoteichoic acid inhibits delayed-type hypersensitivity reactions via the platelet-activating factor receptor.

J. Clin. Invest. 115(10) , 2855-61, (2005)

Staphylococcus aureus infections are known triggers for skin inflammation and can modulate immune responses. The present studies used model systems consisting of platelet-activating factor receptor-po...

Platelet-activating factor biosynthesis induced by various stimuli in human HaCaT keratinocytes.

J. Invest. Dermatol. 107(1) , 88-94, (1996)

Platelet-activating factor (PAF) is a potent inflammatory mediator that is thought to play a role in cutaneous inflammation. These studies used mass spectrometry to examine the molecular species of PA...

The secreted protease factor CPAF is responsible for degrading pro-apoptotic BH3-only proteins in Chlamydia trachomatis-infected cells.

J. Biol. Chem. 281(42) , 31495-501, (2006)

Chlamydia trachomatis has evolved a profound anti-apoptotic activity that may aid in chlamydial evasion of host defense. The C. trachomatis anti-apoptotic activity has been correlated with blockade of...

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