Development of a Supply Route for the Synthesis of an iNOS Inhibitor: Complications of the Key SN2 Reaction

G Rassias, SA Hermitage, MJ Sanganee…

文献索引：Galvez-Ruiz, Juan Carlos; Jaen-Gaspar, Javier C.; Castellanos-Arzola, Indira G.; Contreras, Rosalinda; Flores-Parra, Angelina Heterocycles, 2004 , vol. 63, # 10 p. 2269 - 2285

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被引用次数: 2

摘要

... chemistry procedure for the preparation of 8 involved combination of equimolar amounts of 4 and 7 and anhydrous cesium carbonate, in 43 volumes of degassed acetonitrile at 10 °C for 13 ... Laboratory experiments on 5−10 g scale also showed that the volume of acetonitrile ...