Tetrahedron letters

Amino acid-mediated Goldberg reactions between amides and aryl iodides

W Deng, YF Wang, Y Zou, L Liu, QX Guo

文献索引：Deng, Wei; Wang, Ye-Feng; Zou, Yan; Liu, Lei; Guo, Qing-Xiang Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2311 - 2315

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被引用次数: 127

摘要

Transition metal-catalyzed amide arylation is a widely utilized reaction in academic and industrial laboratories and therefore, has been a focus of interest recently. 1 So far significant improvements have been achieved in Pd-catalyzed amide arylation reactions, 2 but it remains hard to apply these reactions to large and industrial scale syntheses due to the high cost of Pd and the difficulty in removing Pd residues from polar reaction products. ... An alternative method for amide ...