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Carbohydrate research

Synthesis of 2′-and 3′-azido-2′, 3′-dideoxyadenosines. Preparative applications of the deoxygenative [1, 2]-hydride shift and β-elimination reactions of O- …

M Kawana, H Kuzuhara

文献索引:Kawana, Masajiro Chemistry Letters, 1981 , p. 1541 - 1542

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被引用次数: 7

摘要

Abstract 2′-Azido-2′, 3′-dideoxyadenosine (9) has been synthesized from adenosine (1) in 6–8 steps. The key intermediate, N 6, O 5′-bis (4, 4′-dimethoxytrityl)-9-(3-deoxy-β-d- threo-pentofuranosyl) adenine (6a), was prepared in a one-flask manner by two methods,(a)