e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Carbohydrate research
Synthesis of 2′-and 3′-azido-2′, 3′-dideoxyadenosines. Preparative applications of the deoxygenative [1, 2]-hydride shift and β-elimination reactions of O- …
Abstract 2′-Azido-2′, 3′-dideoxyadenosine (9) has been synthesized from adenosine (1) in 6–8 steps. The key intermediate, N 6, O 5′-bis (4, 4′-dimethoxytrityl)-9-(3-deoxy-β-d- threo-pentofuranosyl) adenine (6a), was prepared in a one-flask manner by two methods,(a)