Microbially mediated enantioselective ester hydrolyses utilizing Rhizopus nigricans. A new method of assigning the absolute stereochemistry of acyclic 1-arylalkanols

H Ziffer, K Kawai, M Kasai, M Imuta…

文献索引：Ziffer, Herman; Kawai, Ken-ichi; Kasai, Masaji; Imuta, Mitsuru; Froussios, Cleanthis Journal of Organic Chemistry, 1983 , vol. 48, # 18 p. 3017 - 3021

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被引用次数: 67

摘要

The fungus Rhizopus nigricans has been used to effect the enantioselective hydrolysis of 22 acetates of acyclic 1-arylalkanols. The absolute stereochemistry of all the chiral alcohols formed can be accounted for by a rule which is based on the relative sizes of substituents on the carbinol carbon. The relative sizes of substituents deduced from these hydrolyses have been compared with those assigned from Horeau's method for the same compounds and ...