Bromination of the 2-aminonitrofurylthiazole IVc and its acetyl derivative V gave monobromo compounds. These are considered to be the 5-bromothiazoles because of the inactivity of the nitrofuran ring toward bromination and the ease with which aminothiazoles with an unoccupied 5-position undergo halogenati~ n.~ Acetylation of 2-amino-5-bromo-4-(5-nitro-2- furyl) thiazole (VIa) provided an alternate route to the acetyl bromo compound VIb and ...
![N-acetyl-N-[4-(5-nitro-2-furyl)-1,3-thiazol-2-yl]acetohydrazide结构式](https://image.chemsrc.com/caspic/489/91091-92-8.png)
![N-[5-bromo-4-(5-nitro-2-furyl)-1,3-thiazol-2-yl]acetamide结构式](https://image.chemsrc.com/caspic/462/51948-56-2.png)
