Nature Cell Biology 2017-07-17

Dll4 and Notch signalling couples sprouting angiogenesis and artery formation

文献索引：10.1038/ncb3555

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摘要

Pitulescu et al. show that Dll4–Notch signalling induces a cell fate switch to specify future arterial endothelial cells among the progeny of tip cells, linking sprouting angiogenesis and artery formation.