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Synthesis and biological activity of N-alkoxybenzenesulfonyl-5-halouracils

MA Kaldrikyan, VA Geboyan, YZ Ter-Zakharyan…

文献索引:Kaldrikyan, M. A.; Geboyan, V. A.; Ter-Zakharyan, Yu. Z.; Paronikyan, R. V.; Garibdzhanyan, B. T.; et al. Pharmaceutical Chemistry Journal, 1986 , vol. 20, # 8 p. 540 - 544 Khimiko-Farmatsevticheskii Zhurnal, 1986 , vol. 20, # 8 p. 928 - 932

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摘要

The position of the benzenesulfonyl grouping was established by mass spectrometry. In addition to the molecular peak at 300, ions were found having m/z 236 (M--SO2), 193 (236-- HNCO). The presence of the latter ion, and the absence of an ion with m/z 213, showed that the 4-methoxybenzenesulfonyl group is located in the 1-position of (Ia).