The mixed open-chain imide N-(3-chloro-4-hydroxyphenyl-thesized by base-catalyzed condensation of the imidates acety1) fumarate (l), named coniothyriomycin, was isolated as 12a-f with acid chlorides 6a-c or the mixed anhydride 21. metabolite of the fungus Coniothyrium. The natural product The compounds 1 and 13-15 were shown to posess remark-1 and the analoguos imides 13-15 and 22-24 have been syn-able fungicidal and ...