Wirkstoffe aus Pilzen, I. Isolierung, Synthese und biologische Wirkung von Coniothyriomycin sowie Synthese und Biotestung analoger offenkettiger Imide

K Krohn, C Franke, PG Jones, HJ Aust…

Index: Krohn, Karsten; Franke, Claudia; Jones, Peter G.; Aust, Hans-Juergen; Draeger, Sigfried; Schulz, Barbara Liebigs Annalen der Chemie, 1992 , # 8 p. 789 - 798

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Abstract

The mixed open-chain imide N-(3-chloro-4-hydroxyphenyl-thesized by base-catalyzed condensation of the imidates acety1) fumarate (l), named coniothyriomycin, was isolated as 12a-f with acid chlorides 6a-c or the mixed anhydride 21. metabolite of the fungus Coniothyrium. The natural product The compounds 1 and 13-15 were shown to posess remark-1 and the analoguos imides 13-15 and 22-24 have been syn-able fungicidal and ...