European Journal of Organic Chemistry 2017-10-09

Brønsted Acid Catalyzed Domino Aza-Piancatelli Rearrangement/Michael Reaction: Construction of 1,4-Benzodiazepin-5-ones in One Pot

Kiranmai Nayani, Radhika Cinsani, Anwar Hussaini SD, Prathama S. Mainkar, Srivari Chandrasekhar

文献索引：10.1002/ejoc.201700957

摘要

A facile one-pot method has been developed for the construction of 1,4-benzodiazepin-5-ones through a Brønsted acid catalyzed domino aza-Piancatelli rearrangement/Michael reaction between furfuryl carbinols and o-aminobenzamides under mild conditions.