Tetrahedron Letters

Studies on the total synthesis of macrolactin A. A stereoselective synthesis of the C 3–C 13 and C 14–C 24 fragments

S Li, R Xu, D Bai

文献索引：Li, Shukun; Xu, Rui; Bai, Donglu Tetrahedron Letters, 2000 , vol. 41, # 18 p. 3463 - 3466

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被引用次数: 20

摘要

Synthetic studies towards the C3–C13 (2) and C14–C24 (3) segments of the potent antiviral and antitumor compound macrolactin A (1) are presented. Segment 2 was constructed via a convergent and facile approach, exploiting Wittig olefination to generate the sensitive E, Z-