The Journal of organic chemistry

Bismuth triflate-catalyzed three-component Mannich-type reaction

T Ollevier, E Nadeau

文献索引：Ollevier, Thierry; Nadeau, Etienne Journal of Organic Chemistry, 2004 , vol. 69, # 26 p. 9292 - 9295

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被引用次数: 142

摘要

Bismuth triflate catalyzes the Mannich-type reaction of a variety of in situ generated aldimines using aldehydes, anilines, and silyl enol ethers in a three-component reaction. The reaction proceeds rapidly and affords the corresponding protected β-amino ketones in high yields (up to 94%).