Bulletin of the Chemical Society of Japan

Syntheses of 2-Amino-3, 4-dimethyl-3H-imidazo [4, 5-f] quinoline and Its Related Compounds

H Kasai, S Nishimura

文献索引：Kasai, Hiroshi; Nishimura, Susumu Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 7 p. 2233 - 2235

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被引用次数: 16

摘要

The strongly mutagenic compound, 2-amino-3, 4-dimethyl-3H-imidazo [4, 5-f] quinoline (Me- IQ), isolated from broiled sardines was synthesized from 6-amino-7-methylquinoline. Several structurally related compounds were also synthesized to clarify the structure-activity relationship. Some of them also showed strong mutagenic activity towards Salmonella typhimurium TA98.