Chemistry Letters

Structure and chemical synthesis of Me-IQ, a potent mutagen isolated from broiled fish.

H Kasai, Z Yamaizumi, K Wakabayashi, M Nagao…

文献索引：Kasai, Hiroshi; Yamaizumi, Ziro; Wakabayashi, Keiji; Nagao, Minako; Sugimura, Takashi; et al. Chemistry Letters, 1980 , p. 1391 - 1394

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被引用次数: 97

摘要

Structure of a mutagenic compound (Me-IQ) isolated from broiled fish was determined to be 2-amino-3, 4-dimethylimidazo [4, 5-f] quinoline based on the mass-, UV-and 1 H-NMR- spectra and chemical synthesis. Me-IQ showed strong mutagenic activity towards Salmonella typhimurium TA98 in the presence of S-9 mix.