Chemistry–A European Journal

Investigations on the Iron??Catalyzed Asymmetric Sulfide Oxidation

J Legros, C Bolm

文献索引：Legros, Julien; Bolm, Carsten Chemistry - A European Journal, 2005 , vol. 11, # 4 p. 1086 - 1092

全文：HTML全文

被引用次数: 211

摘要

Abstract The development of an enantioselective sulfide oxidation involving a chiral iron catalyst and aqueous hydrogen peroxide as oxidant is described. In the presence of a simple carboxylic acid, or a carboxylate salt, the reaction affords sulfoxides with remarkable enantioselectivities (up to 96% ee) in moderate to good yields. The influence of the structure of the additive on the reaction outcome is reported. In the sulfoxide-to-sulfone oxidation a ...