Synthesis of Potential Anticancer Agents. IX. 9-Ethyl-6-substituted-purines2

JA Montgomery, C Temple Jr

文献索引：Montgomery; Temple Journal of the American Chemical Society, 1957 , vol. 79, p. 5238,5241

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被引用次数: 78

摘要

Several 9-ethyl-6-substituted-purines have been prepared from 6-chloro-9-ethylpurine. This compound was prepared by reaction of 5-ami11o-4, 6-dichloropyrimidine with ethylamine and cyclization of the resulting 5-amino-6-chloro-4-ethylaminopyrimidine to the purine by the use of diethoxymethyl acetate.