Tetrahedron letters

An efficient route for commercially viable syntheses of furan-and thiophene-anellated β-hydroxychalcones

PP Yadav, G Ahmad, R Maurya

文献索引：Yadav, Prem P.; Ahmad, Ghufran; Maurya, Rakesh Tetrahedron Letters, 2005 , vol. 46, # 34 p. 5621 - 5624

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被引用次数: 11

摘要

An efficient route for the syntheses of β-hydroxychalcones containing benzofuran and benzothiophene rings is described. Isoxazolines obtained from oxime–olefin cycloadditions were reduced under pressure to a mixture of products. Isoxazoles obtained from Claisen aroylation of an ester and subsequent acid cyclization, or from isoxazolines via DDQ- mediated dehydrogenation, were subjected to catalytic hydrogenation followed by ...