Chemical Communications

No-carrier-added [18 F] fluoroarenes from the radiofluorination of diaryl sulfoxides

JH Chun, CL Morse, FT Chin, VW Pike

文献索引：Chun, Joong-Hyun; Morse, Cheryl L.; Chin, Frederick T.; Pike, Victor W. Chemical Communications, 2013 , vol. 49, # 21 p. 2151 - 2153

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被引用次数: 14

摘要

No-carrier-added [18F] fluoroarenes were synthesized through the radiofluorination of diaryl sulfoxides with [18F] fluoride ion. Diaryl sulfoxides bearing a para electron-withdrawing substituent readily gave the corresponding 4-[18F] fluoroarenes in high RCYs. This process broadens the scope for preparing novel 18F-labeling synthons and PET radiotracers.