Tetrahedron

One-pot synthesis of unsymmetrical benzils and N-heteroarenes through nucleophilic aroylation catalyzed by N-heterocyclic carbene

Y Suzuki, M Murofushi, K Manabe

文献索引：Suzuki, Yumiko; Murofushi, Mai; Manabe, Kei Tetrahedron, 2013 , vol. 69, # 2 p. 470 - 473

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被引用次数: 4

摘要

An efficient one-pot synthesis of various unsymmetrical benzils via N-heterocyclic carbene (NHC)-catalyzed aroylation of N-phenylimidoyl chlorides with aromatic aldehydes followed by acidic hydrolysis has been developed. The one-pot procedure was extended to synthesis of quinoxalines and pyrazines by condensation/annulation of unsymmetrical benzils generated in situ with diamines.