The NMR spectra of a wide variety of substi- tuted isoquinoline derivatives have been extensively reported,'-' largely owing to the abundance of isoquinoline alkaloids and their vaned biological activities9 In the course of our medicinal research, we had occasion to synthesize fifteen new iso- quinoline derivatives which are reported here. ... The 'H and I3C NMR assignments are sum- marized in Tables 14. The assignments of the 'H NMR chemical shifts were ...
