Tetrahedron Letters

A convenient synthesis of 5-arylamino-4H-pyran-4-ones using palladium-catalyzed amination

J Farard, C Logé, B Pfeiffer, B Lesur, M Duflos

文献索引：Farard, Julien; Loge, Cedric; Pfeiffer, Bruno; Lesur, Brigitte; Duflos, Muriel Tetrahedron Letters, 2009 , vol. 50, # 41 p. 5729 - 5732

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被引用次数: 11

摘要

A concise approach to 5-arylamino-4H-pyran-4-ones is described via palladium-catalyzed amination reaction. The methodology involved in this Letter is based on protection/ deprotection protocols and on manipulation of the 5-hydroxy group of readily available kojic acid. It would provide a new entry to a range of 5-arylamino-4H-pyran-4-ones via Buchwald– Hartwig-type amination reaction on 4H-pyran-4-one unit.