New furanoflavanoids, intestinal α-glucosidase inhibitory and free-radical (DPPH) scavenging, activity from antihyperglycemic root extract of Derris indica (Lam.)

…, PP Reddy, KS Babu, AZ Ali, K Madhusudana…

文献索引：Ranga Rao; Tiwari, Ashok K.; Prabhakar Reddy; Suresh Babu; Ali, Amtul Z.; Madhusudana; Madhusudana Rao Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 14 p. 5170 - 5175

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被引用次数: 52

摘要

A bioassay-guided fractionation and chemical examination of antihyperglycemic root extract of Derris indica resulted in isolation and characterization of two new furanoflavanoids (1, 2) along with thirteen known compounds (3–15). Their structures were determined on the basis of extensive spectroscopic (IR, MS, 1D and 2D NMR) data analysis and by comparison with the literature data. All the compounds were tested in vitro for intestinal α-glucosidase ...