Cyclocondensation Reactions between 2??Acyl??3??indoleacetic Acid Derivatives and Phenylglycinol: Enantioselective Synthesis of 1??Substituted Tetrahydro?螃漫? …

…, V Elias, N Llor, E Molins, J Bosch

文献索引：Amat, Mercedes; Subrizi, Fabiana; Elias, Viviane; Llor, Nuria; Molins, Elies; Bosch, Joan European Journal of Organic Chemistry, 2012 , # 9 p. 1835 - 1842

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被引用次数: 2

摘要

Abstract Cyclocondensation reactions between a variety of 2-acyl-3-indoleacetic acid derivatives and (R)-phenylglycinol were studied. Successful results were obtained from N- alkyl keto acid derivatives. The resulting tetracyclic lactams provide straightforward access to enantiopure 1-substituted tetrahydro-β-carboline alkaloids.