Green Chemistry

Efficient copper-catalyzed N-arylations of nitrogen-containing heterocycles and aliphatic amines in water

X Li, D Yang, Y Jiang, H Fu

文献索引：Li, Xufeng; Yang, Daoshan; Jiang, Yuyang; Fu, Hua Green Chemistry, 2010 , vol. 12, # 6 p. 1097 - 1105

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被引用次数: 43

摘要

A simple and efficient copper-catalyzed method has been developed for N-arylations of nitrogen-containing heterocycles and aliphatic amines in water. The protocol uses (1E, 2E)- oxalaldehyde dioxime (OADO) as the ligand, and water as the solvent, and shows good tolerance towards various functional groups.