In vitro affinities of various halogenated benzamide derivatives as potential radioligands for non-invasive quantification of D 2-like dopamine receptors
…, H Hübner, P Gmeiner, G Gründer, F Rösch
文献索引：Stark, Daniela; Piel, Markus; Huebner, Harald; Gmeiner, Peter; Gruender, Gerhard; Roesch, Frank Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 21 p. 6819 - 6829
Benzamide derivatives as radiotracers have played an important role in diagnosing malfunction in dopaminergic neurotransmission. A variety of halogenated and two unsubstituted benzamide derivatives were synthesised and their in vitro affinities to dopaminergic, serotonergic and adrenergic receptors and their lipophilicities were determined. As references IBZM (3), raclopride (4) and FLB457 (5) were tested as well. ...
