Rhodium-Catalyzed Cross-Coupling Reaction of Arylboronates and Diazoesters and Tandem Alkylation Reaction for the Synthesis of Quaternary α, α-Heterodiaryl …
A rhodium-catalyzed one-pot three-component coupling reaction was developed for the synthesis of quaternary α, α-heterodiaryl carboxylic esters. This reaction involves cross- coupling of the arylrhodium (I) complexes with α-aryldiazoacetates to form oxa-π- allylrhodium complexes. With KO t Bu and alkyl halides, tandem alkylation of the allyl complex occurs to form a quaternary stereocenter at the carbenic carbon.
