e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Organic letters
Rhodium-Catalyzed Cross-Coupling Reaction of Arylboronates and Diazoesters and Tandem Alkylation Reaction for the Synthesis of Quaternary α, α-Heterodiaryl …
A rhodium-catalyzed one-pot three-component coupling reaction was developed for the synthesis of quaternary α, α-heterodiaryl carboxylic esters. This reaction involves cross- coupling of the arylrhodium (I) complexes with α-aryldiazoacetates to form oxa-π- allylrhodium complexes. With KO t Bu and alkyl halides, tandem alkylation of the allyl complex occurs to form a quaternary stereocenter at the carbenic carbon.
