Organic process research & development

A convenient method of synthesis of unsymmetrical urea derivatives

G Groszek

文献索引：Groszek, Grazyna Organic Process Research and Development, 2002 , vol. 6, # 6 p. 759 - 761

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被引用次数: 18

摘要

A method for the preparation of unsymmetrical urea derivatives that may contain functional groups such as hydroxyl, amine, amide, and carboxyl is described. The method consists of a one-pot modified Curtius rearrangement starting with appropriate aromatic acid chloride and carried out in a nonaqueous system