A new series of N-[(2-chloro-8-methylquinolin-3-yl) methyl]-(substituted)-aniline/butylamine/ cyclohexylamine/benzylamine derivatives (4a–p) was synthesized by nucleophilic substitution reaction of 2-chloro-3-(chloromethyl)-8-methylquinoline 3 with various aliphatic and aromatic amines in absolute ethanol in the presence of triethylamine (TEA). The newly synthesized secondary amines were characterized by the combined use of IR, 1H NMR, ...
