Isoxazole amino-acids as glutamic acid agonists. Synthesis of some analogues and homologues of ibotenic acid

JJ Hansen, P Krogsgaard-Larsen

文献索引：Hansen; Krogsgaard-Larsen Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 8, p. 1826 - 1833

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被引用次数: 39

摘要

(,)-α-Amino-3-hydroxy-4-methylisoxazol-5-ylacetic acid (4-methylibotenic acid)(14) was prepared amination of 3-methoxy-4-methylisoxazol-5-ylacetic acid (12) with- mesitylenesulphonyloxyamine.(,)-α-Amino-3-hydroxyisoxazol-5-ylpropionic acid (homoibotenic acid)(17),(,)-α-amino-4-bromo-3-hydroxyisoxazol-5-ylpropion