Isoxazole amino-acids as glutamic acid agonists. Synthesis of some analogues and homologues of ibotenic acid

JJ Hansen, P Krogsgaard-Larsen

Index: Hansen; Krogsgaard-Larsen Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 8, p. 1826 - 1833

Full Text: HTML

Citation Number: 39

Abstract

(,)-α-Amino-3-hydroxy-4-methylisoxazol-5-ylacetic acid (4-methylibotenic acid)(14) was prepared amination of 3-methoxy-4-methylisoxazol-5-ylacetic acid (12) with- mesitylenesulphonyloxyamine.(,)-α-Amino-3-hydroxyisoxazol-5-ylpropionic acid (homoibotenic acid)(17),(,)-α-amino-4-bromo-3-hydroxyisoxazol-5-ylpropion