Tetrahedron

Studies on SRN1 reactions-9: A new access to the isoquinoline ring system

R Beugelmans, J Chastanet, G Roussi

文献索引：Beugelmans, Rene; Chastanet, Jacqueline; Roussi, Georges Tetrahedron, 1984 , vol. 40, # 2 p. 311 - 314

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被引用次数: 25

摘要

The SRN1 reaction between o-halogeno-benzylamines and enolates derived from a series of ketones and aldehydes affords 1, 2 dihydro-isoquinolines from which are obtained (i) the isoquinoline derivatives, either spontaneously or by treatment on Pd-C and (ii) the 1, 2, 3, 4 tetrahydro-isoquinoline derivatives after sodium borohydride reduction.