Chemical transformations of 6-[(1-methyl-4-nitro-5-imidazolyl)-thio] purine (azathioprine)

PM Kochergin, EV Aleksandrova…

文献索引：Kochergin; Aleksandrova; Korsunskii Chemistry of Heterocyclic Compounds, 2000 , vol. 36, # 3 p. 311 - 318

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被引用次数: 1

摘要

Abstract The chemical transformations of 6-[(1-methyl-4-nitro-5-imidazolyl) thio] purine (azathiopurine)—hydrogenation, acetylation, alkylation by lower alkyl halides at positions 7 and 9 of the purine ring, hydrolytic cleavage at the C (6)− S and S− C (5) bonds—were