Tetrahedron

Facile transformation of esters to nitriles

Y Suzuki, K Moriyama, H Togo

文献索引：Suzuki, Yusuke; Moriyama, Katsuhiko; Togo, Hideo Tetrahedron, 2011 , vol. 67, # 41 p. 7956 - 7962

被引用次数: 18

摘要

Various esters were efficiently converted into the corresponding nitriles in good yields by the treatment with sodium diisobutyl-tert-butoxyaluminium hydride (SDBBA-H), followed by treatment with molecular iodine in aq ammonia. The present one-pot method is very efficient and practical for the conversion of various aromatic and aliphatic esters into the corresponding nitriles.

10287-53-3

对-N,N-二甲氨基苯甲酸乙酯

~16%

1197-19-9

4-(二甲胺基)苄腈

~71%

~80%

~46%

~73%

~92%

~88%

~82%

~83%

~78%

~72%

~71%

~82%

~75%

~0%

~13%

~80%

~27%

~80%

~76%

~70%

~72%

~86%

~74%

~84%

~79%

~72%

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