Chemical Communications

A general and selective copper-catalyzed reduction of secondary amides

S Das, B Join, K Junge, M Beller

文献索引：Das, Shoubhik; Join, Benoit; Junge, Kathrin; Beller, Matthias Chemical Communications, 2012 , vol. 48, # 21 p. 2683 - 2685

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被引用次数: 36

摘要

Reduction of amides constitutes an important synthetic method for the preparation of functionalized amines both on the laboratory as well as on the industrial scale. Until today, often traditional boron and aluminium hydride-mediated reductions prevail for such processes. 1 Tedious product purification and concomitant formation of salt by-products are disadvantages of these stoichiometric procedures. In contrast, catalytic methods offer more versatile strategies for selective ...