Selective ortho and benzylic functionalization of secondary and tertiary p-tolylsulfonamides. Ipso-bromo desilylation and Suzuki cross-coupling reactions
... Volume: Page ... Figure 3 2 H NMR spectra of products obtained from metalation (n-BuLi (1.1 equiv)/THF/0 °C)/CD 3 OD quench (10 equiv/0 °C ... 17 To explore the effect of additive, 1 was treated with n-BuLi/TMEDA (1:1; 2.2 equiv/THF/0 °C/15 min) followed by CD 3 ...