Tetrahedron

Effect of branching in alkylgroups of tertiary amines on their performance as catalysts in the high pressure promoted Baylis-Hillman reaction

RJW Schuurman, A d Linden, RPF Grimbergen…

文献索引：Schuurman; Linden; Grimbergen; Nolte; Scheeren Tetrahedron, 1996 , vol. 52, # 24 p. 8307 - 8314

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被引用次数: 9

摘要

Receptors 1 were tested as catalysts for the high pressure promoted Baylis-Hillman reaction. Surprisingly most of the compounds were found to be catalytically inactive. With model compounds (simple acyclic tertiary amines) it could be shown that tertiary amines with branches at their α-carbon atoms show a remarkable decreased activity. It is proposed that the branches prevent attack of the lone pair of the amine on the double bond of the alkene ...