Tetrahedron letters

Palladium-catalyzed C–O bond formation: direct synthesis of phenols and aryl/alkyl ethers from activated aryl halides

G Chen, ASC Chan, FY Kwong

文献索引：Chen, Guoshu; Chan, Albert S.C.; Kwong, Fuk Yee Tetrahedron Letters, 2007 , vol. 48, # 3 p. 473 - 476

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被引用次数: 69

摘要

A simple and efficient palladium-catalyzed carbon–oxygen bond formation is reported. The palladium-tri-tert-butylphosphine complex was found to be effective in converting haloarenes to corresponding substituted phenols. This methodology offers a direct transformation of aryl halides to phenols, as well as the straightforward application to generate a wide variety of diaryl or alkyl/aryl ethers.