Highly efficient, practical approach to natural taxol

JN Denis, AE Greene, D Guenard…

文献索引：Denis, Jean-Noel; Greene, Andrew E. Journal of the American Chemical Society, 1988 , vol. 110, # 17 p. 5917 - 5919

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被引用次数: 632

摘要

Taxol (I)] is an exceptionally promising cancer chemotherapeutic agent with an unusually broad spectrum of potent antileukemic and tumor-inhibiting activity. 2 Taxol is active in vivo against P-388, P-1534, and L-1210 mouse leukemias, B-16 melanocarcinoma, Lewis lung carcinoma, sarcoma 180, and CX-I colon, LX-I lung, and MX-I breast~ enographs.'-~ The bark